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Cardiomyopathy in Patient with Malignant Lymphoma: A Case Report

Author : D.Y. Pertiwi, T.T. Dewi, I. Rakhmawati , I.R. Hidayat, A.P. Ayu, D. Rostiati
Upload Date : 19-04-2018

Introduction: Malignant lymphoma with cardiac metastases is one of the least investigation subject in oncology. Cardiac involvement are found in 20% to 25% of patient with lymphoma. Examination of cardiac involvement can be show as cardiomyopathy. Cardiomyopathy caused by malignant lymphoma metastase is rarely to find.

Case Presentation: A 42 year old, female presented with fatigue and pallor. She had nodul at right side of neck and became bigger than normal size. She had been diagnosed to suffer from malignant lymphoma after anatomical pathology examination 1 week ago. No history about heart disease and doing chemotherapy.

Her BP was 110/70 mmHg and pulse 120 x/min, regular. Anemia was found in this patient. Systolic murmur, rhonchi and wheezing were not revealed. ECG showed tachycardia sinus rhytm.

Echocardiography showed dilated left atrial (4.05 cm) and left ventricle . Hypokinetic global with ejection fraction 28.99%, diastolic dysfunction grade 1 with MV E/A ratio 0.66, TAPSE 1.45. She was diagnosed to suffer from cardiomyopathy with malignant lymphoma and anemia.

Discussion: In this case, factor related malignant lymphoma is family history of cancer. Eating fast food can affect this condition.

Malignant lymphoma metastase make myosit injury which decrease contractility and stroke volume. It causes left ventricle dilatation and decrease forward cardiac output. In this patient symptom like pulmonary and systemic congestion does not yet exist. It maybe new onset or personal compensation.

Cardiac magnetic resonance imaging (MRI) is often helpful in evaluation of dilated cardiomyopathy.

Conclusion: The incidence of Malignant lymphoma may be presented in patient with cardiomyopathy.

KEYWORDS : Malignant Lymphoma, Cardiomyopathy

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