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Left Ventricular Ejection Fraction in correlation with In Hospital Mortality in ACS Patients: SCIENCE Registry Sub-Study

Author : B.A. Prabowo, H.P. Bagaswoto, N. Taufiq, B.Y. Setianto
Upload Date : 19-04-2018

Background Left Ventricular Ejection Fraction (LVEF) is one of prognostic factor that determine risk in STEMI patients. Data regarding Left Ventricular Ejection Fraction (LVEF) that determine mortality risk in all spectrum of ACS (Acute Coronary Syndrome) has not been established.

Aim : To correlate LVEF with mortality risk in ACS Patient

Methods : This prospective cohort study was performed as a substudy on the SCIENCE (Sardjito Cardiovascular Intensive Care) and ACS registry from January 2017 until October 2017. Patients that met inclusion criterias (diagnosed as ACS, got routine blood exam checked at admission) classified to two categories based on Left Ventricular Ejection Fraction (LVEF) Preserved EF (EF>45%) and reduced EF (EF<45%). We correlate proportion of mortality in each groups using ChiSquare model.

Results : Total of 407 patients diagnosed as ACS , whether STEACS or NSTEACS included in our study. As many as 143 patients (35 %) included in reduced EF whether 264 patients (64.9%) were in preserved EF. Baseline characteristic in both group showed us no significant differences. Relative Risk (RR) was 1,56 with p value 0,143 (95% CI), considered statistically not significant.

Conclusion : There is increase risk of inhospital mortality in patient with reduced LVEF but statistically not significant

KEYWORDS : LVEF, Acute Coronary Syndrome, in hospital mortality

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