Age, High Density Lipoprotein Cholesterol and Triglycerides are Correlated with Triple-Vessel Coronary Artery Disease

Author : Y.S. Pratama, U. Bahrudin, S. Sungkar, I. Uddin
Upload Date : 19-04-2018

Background: Male, older age, diabetes, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglycerides (TG) are common risk factors of coronary artery disease (CAD). However, correlation between those risk factors and the presence of CAD triple-vessel disease (3VD) remains unclear. Purpose of this study was to know the correlation between common risk factor of CAD and the presence of 3VD.

Methods: A retrospective study of 59 patients with ST-elevation myocardial infarction (STEMI) underwent primary percutaneous coronary intervention (PPCI) was performed from January to September 2017 at the Dr. Kariadi Hospital.

Results: The mean age of patients was 56.78±10.25 years old with 82.5% of them were male. Age ≥52 years old and low level of HDL-C were correlated with CAD 3VD (r=0.284, p=0.029 and r=0.288, p=0.035, respectively), while low level of TG had an inverse correlation (r=0.286, p=0.038). Male more common had CAD 3VD than female, although statistics analysis was not significant (r=0.172, p=0.193). Other risk factors diabetes and level of LDL-C had no significant correlation with CAD 3VD (r=0.057, p=0.69; and r= -0.007, p=0.958, respectively).

Conclusion: These data suggest that age ≥52 years old and low HDL-C level are correlated with presence of CAD 3VD, while low level of TG had an inverse correlation. Further study is warranted to confirm this result.

KEYWORDS : coronary artery disease, age, triglycerides, HDL-C, triple-vessel disease

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