Advanced

Resolution of ST-Segment, Pain Level, and Arrythmia as A Tool For Assessing The Efficacy of Reperfusion Therapy in STEMI Patient Hospital Kanjuruhan

Author : A. N. Lukito, G. A. Pawintri , A. B. Santoso
Upload Date : 19-04-2018

Background : Acute coronary syndrome is a major cardiovascular problem that causes increase mortality and morbidity, including ST segment elevation myocardial infarction (STEMI). Treatment for STEMI patients in Kanjuruhan Hospital using pharmacotheraphy reperfusion (Streptokinase) as Primary PCI action takes more than 2 hours for prepare until transfer to PCI center. The aim of study is to prove the rate of success of streptokinase reperfusion therapy by looking for signs of thrombolytic efficacy.

Methods : Cohort study had been done to compare the effect of pre and post streptokinase therapy with resolution of ST segments, pain relief, and reperfusion arrhythmia. Paired sample t-test and chi-square test was used to analyze the data sample. The study was set in emergency department setting from April-July 2017.

Results : 16 patients had met the criteria. Paired sample t-test showed p=0.011 means that a significant difference of pain scale before and after thrombolytic. Pain relief is associated with ST segment resolution (p=0.05). 50% of the patients showed complete resolution (> 70% ST-resolution), 30% of the patients showed partial resolution (30-70% ST-resolution), and 20% of the patients with no resolution (<30% ST-resolution). 20% of the patients with no resolution also showed no decrease of pain scale > 50% (p=0.05). 37.5% of patients showed arrhythmias, 4 arrhythmias occur in partial resolution group and 1 artimia occurs in the no resolution group. There are 3 PVC patients, 1 with PVC manifesting VT, 1 with VT, 1 with AV-block (p=0.108). Therefore the arrhythmias did not correlate with ST-resolution, and if only arrhythmias (except PVC) not always showed the successes of reperfusion.

Conclusion : Streptokinase reperfusion does affects the successes of STEMI patients treatment. Analysis of pain score, ST segment resolution, and arrythmia are useful to decide the sucessful of reperfusion.

KEYWORDS : Reperfusion, Streptokinase, ACS, STEMI


Save Item
Download
Similar Articles

Predictors of In-Hospital Mortality of ST-Segment Elevation Myocardial Infarction Patients Presenting Beyond First 12 Hours from Symptom Onset: A Two Year Retrospective Analysis National Cardiac Centre Harapan Kita (NCCHK)(W. Firmanda, D. K. Firmansyah, Rizki1, Y. Hendarto, B. Widyantoro, D. Zamroni,I. Firdaus, D. A. Ju)

Effect of Percutaneous Coronary Intervention on Length Of Stay in Late Onset (>12 hours) STEMI Patients with High Degree AV Block.(D. D. A. Sakti, D. Firman, S. Dharma)

Comparison of Cadillac Risk Score and GRACE Risk Score to Predict In-Hospital Major Adverse Cardiac Events in Post Primary Percutaneous Coronary Intervention Patients (A. A. Asrial, A. Pudjiastuti, Haryadi, L. Raharjoyo, N. Virginia, Y. Herry)

Correlation between Dietary Fat Intake and Physical Activity to Small Dense Low Density Lipoprotein Level in Acute Coronary Syndrome Patients(A. Pudjiastuti, A. A. Asrial, A. Sariningrum, Haryadi, S. N. Sofia)

Platelet Indices, Infarct Site and In-Hospital Major Adverse Cardiac Events in ST Elevation Myocardial Infarction Patients Undergoing Primary PCI.(A. A. Asrial, A. Pudjiastuti, Haryadi, L Raharjoyo, N. Virginia, Y. Herry)

Correlation between Left Ventricular Ejection Fraction and Zwolle Risk Score in Post Primary Percutaneous Coronary Intervention Patients(A. Pudjiastuti, A. A. Asrial, A. Sariningrum, S. N. Sofia)

Is Admission Hyperglycemia Associated with Reduced Ejection Fraction in ST elevation Myocardial Infarction without Diabetes?(S.P.I Nasruddin , A.A Nursidiq, N. Purwaningtyas. A. Sukmawarti, G. S. Putri)

Comparison of TIMI Flow Between Streptokinase and Alteplase in Patients with ST Elevation Myocardial Infarction After Successful Fibrinolytic at Haji Adam Malik General Hospital Medan(D. Ashrinda, R. Hasan, C. A. Andra, Z. Mukhtar, H. Hasan)

White Blood Cell Count to Mean Platelet Volume Ratio as a Novel Non-Invasive Marker Predicting Short-term Outcomes in Patients with Non-ST Elevation Myocardial Infarction(Y. Saragih, B. Napitupulu, A.N. Nasution, A.H. Raynaldo, H. Hasan)

Resolution of ST-Segment Depression in Reciprocal Leads as a Predictor of Mayor Adverse Cardiac Event for ST-Segment Elevation Myocardial Infarction Treated by Fibrinolytic Therapy(A. S. Adhitya, H. Hasan, A. Sitepu, Z. Mukhtar)

Correlation between Tpeak - Tend Interval and Myocardial Blush Grade Value in Anterior ST-Elevation Myocardial Infarct Patient(R.P. Kaneko, N. Taufiq, E. Maharani.)

Relationship Of Platelet Distribution Width And Mean Platelet Volume with ST Segmen Resolution After Fibrinolytics On ST Elevation Myocardial Infarction Patients at Haji Adam Malik General Hospital Medan(D. Ashrinda, H. Hasan, N. Z. Akbar, Z. Mukhtar)

Predictors of Hospital Length of Stay Prolongation in Patients with ST-Segment Elevation Myocardial Infarction in Cardiovascular Care Unit Sardjito General Hospital(I.H. Sulistya , H. P. Bagaswoto , N. Taufiq , B. Y. Setianto )

Profile Patient with ST-Elevation Myocardial Infarction Underwent Percutaneous Coronary Intervention at Kariadi Hospital(Y.S. Pratama, S. Sungkar, A. Yudanto, S. Rifqi)

Clinical Profile of patients with Acute Coronary Syndrome in Public Hospital in Bekasi, West Java, Indonesia(B.A.Pratama, J.S. Purnama, K. Priyantoro)

Diagnosing and Treating Left Bundle Branch Block ECG Finding as An Acute Coronary Syndrome Event in Rural Hospital of East Sumba: A Case Report(T.S.R. Sembiring)

Ventricular Tachycardia in Doubt : Usefulness of Brugada and R Wave Peak Time Criteria(Albertus , M. Setiawan )

Transient Segment ST Elevation: Spontaneous Coronary Reperfusion(A.Jalaludinsyah, T.Wasyanto)

Regional Pericarditis with Reciprocal ECG Changes Mimicking Inferior STEMI(G. M. Rahman, M.Y. Alsagaff)

A Case Report: Transient ST Elevation Myocardial Infarction After Initial Treatment in Emergency Department(R.R. Aryanti, Z. Choa, R.D. Tureno, S. H. Putra)

Copyrights 2018 ASMIHA | Managed by Indonesia Medical Event (IME)