Association Between Glycated Hemoglobin with Severity of Coronary Artery Disease in Non-Diabetic Patients

Author : I.M Raditya, M. Syafri, M. Yanni
Upload Date : 19-04-2018

Background : Glycated hemoglobin (HbA1c) is known as one of the diagnostic markers of diabetes mellitus, but some hypotheses suggest that HbA1c also plays an important role in the progression of atherosclerosis. Studies that assessed the association of HbA1c levels with the severity of coronary artery disease, particularly in nondiabetics, have not been widely practiced. 

Methods : The study was cross sectional, evaluating the association between HbA1c levels with severity of coronary artery disease assessed with SYNTAX score in patients with nondiabetics acute coronary syndrome at Dr. M. Djamil Hospital who underwent coronary angiography.

Results : Of the 71 patients enrolled in the study, 34 patients were included in the group with low coronary artery disease severity (SYNTAX score ≤22), while 37 patients belonged to the group of intermediate-high coronary artery disease severity (SYNTAX score> 22). There was a significant difference between the mean levels of HbA1c in the group of low coronary artery disease severity and intermediate-high  coronary artery disease severity (5.55 ± 0.29% vs. 5.78 ± 0.32%, respectively) with p <0.002.

Conclusions: HbA1c levels were significantly associated with coronary artery disease severity assessed with SYNTAX Score in nondiabetic acute coronary syndromes patients.

KEYWORDS : coronary artery disease, severity, HbA1c, SYNTAX score, nondiabetics.

Save Item
Similar Articles

Association between Diabetes Mellitus and Micro-RNA34a Expression in Autologous Bone Marrow Stem Cell in Patients with Coronary Heart Disease Undergoing Stem Cell Therapy(M.G.F. Harmani, R. Sukmawan, B. Widyantoro)

The Role of New Two Parameters to Improve Diagnostic Accuracy of Treadmill Exercise Test Detect Significant Coronary Artery Disease(M.A. ffendy, G. R. Endamatriza, B. B. Tiksnadi, M. Akbar, A. Purnomowati, T. A. Aprami)

Differences in Paraoxonase 1 (PON1) and Ox-LDL Serum Level in Coronary Artery Disease and Non Coronary Artery Disease Patients(R. Adriana, Y.H. Oktaviono, D. Soemantri)

Correlation of NT-ProBNP and sST2 level with the Severity of Mitral Stenosis (R. Rozqie, E. Maharani, H. Mumpuni.)

The Relationship Between Fragmented QRS Complex and Coronary Artery Disease in Patient with Total Atrioventricular Nodal Block Requiring Permanent Pacemaker Implantation(M. Rusydi, Y. Yuniadi, S. B. Raharjo, D. Hanafy, D. Yugo)

Distributon of Multiple Vessels Coronary Artery Disease and Risk Factors in Patient with Acute Coronary Syndrome: Study From Sardjito General Hospital Registry(A. Pradhana, H.P. Bagaswoto, N. Taufiq, B.Y. Setianto)

Precordial ST Segment Depression on Admission Electrocardiogram as a Simple Noninvasive Tool for Predicting Coronary Artery Disease Complexity in Patients with Inferior Myocardial Infarction(J. Suganti, A. C. Lubis, A. A. Siregar, A. Sitepu, C. A. Andra, A. N. Nasution, H. Hasan)

The Associtaion between Uric Acid Level with Multivessel Coronary Artery Disease on Patients who Underwent Coronary Angiography in Abdul Wahab Syahranie General Hospital Samarinda(M.D.Pratama, D. Budiono, O.M.S Nasution, D. Herdianto)

Correlation of Lipid Profile with the Severity of Coronary Artery Disease(M.F. Rizky, P.C. Fianirazha, A.H. Rolando, M.W. Hadi, M.N. Afif, S.F. Liliana, S. Imran, U. Ferry )

Age, High Density Lipoprotein Cholesterol and Triglycerides are Correlated with Triple-Vessel Coronary Artery Disease(Y.S. Pratama, U. Bahrudin, S. Sungkar, I. Uddin)

Lipid Profile and It’s Association with Multivessel Coronary Artery Disease on Patients Who Underwent Coronary Angiography in Abdul Wahab Syahranie General Hospital Samarinda(D. Budiono, O.M.S Nasution, M.D.Pratama , D. Herdianto)

Association between Biomarkers and Plaque Vulnerability Detected by Optical Coherence Tomography in Patient with Coronary Artery Disease: a Meta-analysis(U. Bahrudin, R.A. Raharjo, S. Herminingsih, I. Uddin, Hardian, Y. Herry, S. Rifqi)

Copyrights © 2018 ASMIHA | Managed by Indonesia Medical Event (IME)