Thrombocyte-to-Leukocyte Ratio is correlated with Length of Stay in Patients with ST-Elevation Myocardial Infarction Underwent Primary Percutaneous Coronary Intervention

Author : Y.S. Pratama, R. Puspitoadhi, N.A. Tafriend, U. Bahrudin
Upload Date : 19-04-2018

Background: Several studies have shown that complete blood count parameters have role in the prediction of long-term mortality in acute coronary syndrome (ACS). One of simple parameter is thrombocyte-to-leukocyte ratio (TLR), but data about the link between TLR and in-hospital length of stay (LoS) is limited. Purpose of this study was to know the correlation between TLR and LoS in patient with ST-Elevation Myocardial Infarction (STEMI) underwent primary percutaneous coronary intervention (PPCI).

Methods: A total 63 patients with STEMI underwent PPCI from January to September 2017 was recruited in this retrospective study. The haematological data were retrieved from the available electronic medical record.

Results: In this study,median thrombocyte and leukocyte level on admission were 300x103 and 12.5x103, respectively and the median in-hospital LoS was 5 days. The level of thrombocyte was correlated with in-hospital LoS (r=0.286, p= 0.03), while the level of leukocyte was not (r= -0.037, p=0.78). The mean of TLR was 23.94 ± 9.61 and it was correlated with in-hospital LoS (r=0.383, p=0.003). Linear regression analysis showed significant result between TLR and LoS (r2=0.147, coefficient 0.105, 95% CI 0.038-0.172, p=0.003). Limitation in our study were small sample with retrospective method and other cause of the increasement in-hospital LoS was not considered.

Conclusion: Data of this study showed that TLR is correlated with in-hospital length of stay in STEMI patient underwent PPCI. Further study is warranted to investigate the prognostic predictive value of TLR in these patients.

KEYWORDS : platelet-to-leukocyte ratio, in-hospital length of stay, acute coronary syndrome

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