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Correlation between Tpeak - Tend Interval and Myocardial Blush Grade Value in Anterior ST-Elevation Myocardial Infarct Patient

Author : R.P. Kaneko, N. Taufiq, E. Maharani.
Upload Date : 19-04-2018

Background  : Anterior ST-Elevation Myocardial Infarction (STEMI) is one of the clinical manifestation of Coronary Heart Disesae. In STEMI condition, there is a condition of transmural dispersion of repolarization and microvascular dysfunction. The Tpeak-Tend interval is an ECG parameter that describes the transmural dispersion of repolarization. Myocardial Blush Grade (MBG) is a assessment that can assess microvascular dysfunction. This study aims to examine the correlation between Tpeak-Tend interval and MBG values in anterior STEMI patients.

Methods  : Analytical observational research with cross sectional design. Data were taken consecutive from August to November 2017. The Tpeak-Tend interval assessment was based on ECG results and MBG assessment using Quantitative Blush Evaluator (QuBE) program based on coronary angiography. The Tpeak-Tend interval is divided into Tpeak-Tend interval > 94 millisecond group and Tpeak-Tend interval ≤ 94 millisecond. The MBG values is divided into MBG QuBE 1, MBG QuBE 2 and MBG QuBE 3 groups. Pearson correlation test was used for analysis correlation between Tpeak-Tend interval and MBG value.

Results  : 32 research subjects were enrolled in this study. There were 23 subjects with Tpeak-Tend interval > 94 milliseconds and 9 subjects with Tpeak-Tend interval ≤ 94 milliseconds.  There was a negative correlation with moderate strength between the Tpeak-Tend interval and the MBG value in the anterior STEMI patients (r = -0.501 ; p = 0.004). The Multivariate tests showed Tpeak-Tend intervals as an independent variable against MBG values in anterior STEMI populations (p = 0.035 ; 95%CI : 1.283-12.725).

Conclusion  : There is a negative association with moderate strength between the Tpeak-Tend interval and the MBG values in the anterior STEMI patient and Tpeak-Tend interval is an independent variable against the MBG values in the anterior STEMI patient.

KEYWORDS : ECG, Tpeak-Tend Interval, MBG, Anterior STEMI.

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