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The Correlation between Serum TG/HDL-c Ratio and Arterial Stiffness Using Cardio-Ankle Vascular Index (CAVI) in Overweight or Obese Patients

Author : Andrianus, R. M. Yogiarto, J. N. E. Putranto
Upload Date : 19-04-2018

Background: An increased incidence of cardiovascular disease in line with increased Body Mass Index (BMI). This incident allegedly associated with the process of arterial stiffness and insulin resistance. The effect of increasing the ratio of TG/HDL-c serum as a result of insulin resistance is considered to have an important role on the occurrence of arterial stiffness. Arterial stiffness is one of the independent risk factors on the incidence of cardiovascular disease. Increased arterial stiffness is an important marker in the development of cardiovascular disease and be a predictor of heart attack and stroke. Cardio Ankle Vascular Index (CAVI) is a non-invasive clinical measurement to evaluate arterial stiffnes manner and independent of blood pressure.

Methods: This is a correlational study  with purposive sampling technique. Thirty two subjects participate in this reseach and each subject underwent a CAVI examination to assess arterial stiffness and their blood sample were collected for lipid profile measurement.This study is analyzed with Pearson Correlation Test.

Results: The mean of TG/HDL-c serum level in this study was 3.83 ± 1.4 mg/dL. There is a positive and significant  correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in overweight or obese patients.  (r = 0.455 – 0.528 dan p <0,01).

Conclusion: There was a positive and significant  correlation between TG/HDL-c serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in overweight or obese patients.

KEYWORDS : serum TG/HDL-c ratio, Arterial stiffness, Cardio-ankle vascular index, Overweight, Obese

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