The Difference of Admission Blood Glucose and Its Correlation with In-Hospital Cardiovascular Event on Acute Coronary Syndrome Patients at Mohammad Noer Hospital Pamekasan

Author : A. Romdiyana, H.I. Millisani
Upload Date : 19-04-2018

Background: Acute coronary syndromes (ACS) are life threatening conditions that can punctuate the course of patients with coronary artery disease at any time. High glycaemia on admission predicted increased in-hospital and long-term morbidity and mortality in patients with acute coronary syndrome. This study aimed to analyze the difference of admission blood glucose in each spectrum of acute coronary syndrome and its correlation with in-hospital cardiovascular event.

Methods: This observational cross sectional study was conducted in Mohammad Noer General Hospital from January 2017 to December 2017. Non diabetic patients with acute coronary syndrome got admitted into hospital. The groups were compared to demonstrate the difference between blood glucose in admission and its correlation on in-hospital cardiovascular event (e.g. arrhythmias, heart block, stroke, cardiogenic shock, and death).

Results: In total 63 ACS patients consist of 41 STEMI patients (70% men, mean age 57.2±9.23 years) and 22 UA patients (72% men, mean age 51.1±10.45 years). Mean values of admission blood glucose level in STEMI group and in UA group were 147.92 mg/dl (range 64-296 mg/dl) and 120.09 mg/dl (range 80-205 mg/dl) respectively. Comparison analysis on the mean value of blood glucose level between two groups were done with Independent T test and showed a statistically significant difference between the two groups (p=0.03). In STEMI patients, in-hospital cardiovascular event was significantly associated with stress hyperglycemia (p=0.17). Conversely, in-hospital cardiovascular event was not associated with stress hyperglycemia in UA patients (p=1.00).

Conclusion: The mean admission blood glucose between STEMI patients and UA patients is significantly different. In-Hospital cardiovascular event is significantly associated with stress hyperglycemia in STEMI patients but not in UA patients.

KEYWORDS : acute coronary syndrome, cardiovascular event, admission blood glucose, stress hyperglycemia

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