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Demographic and Clinical Characteristic of Pulmonary Hypertension Patients Hospitalized in National Cardiovascular Center Harapan Kita

Author : P. Almazini*, H.S. Muliawan*, A. Sidarta**, A. Francesca**, M. Asaf**, P.N. Candra**, B.B. Siswanto*
Upload Date : 19-04-2018

Background: Pulmonary hypertension (PH) is a very severe disease of the cardiovascular system and contributes to significant morbidity and mortality. The characteristic of PH patients varies throughout the world therefore obtaining data about demographic and clinical characteristic of PH are important to improve diagnosis and awareness to the disease.

Method: A retrospective study was conducted. Data were obtained from medical registry of patients hospitalized in our center from January 2016 to December 2016.

Results: Total 155 patients with diagnosis pulmonary hypertension were hospitalized in January until December 2016 and were included. Among the 155 patients the median age was 23 years old, range 0-66 years with 97 females (62.6%) and 58 males (37.4%). Almost all of the patients used National Health Insurance (96.1%). The most common presenting symptom was dyspnea in 122 (78.7%). Based on WHO classification of PH, group 1 pulmonary arterial hypertension (PAH) was the most frequent cause of PH (50.9%) and was associated with congenital heart diseases. Group 2, PH due to left heart disease was the second common cause (45.2%) followed by group 4 chronic thromboemboli pulmonary hypertension (CTEPH) (3.2%) and patients with group 3 PH due to lung disease (0.6%). Sixty patients (38.7%) received specific treatment for pulmonary hypertension with pulmonary vasodilator (beraprost, sildenafil). Most of the patients (90.3%) were diagnosed by echocardiography. Right Heart Catheterization (RHC) was available in 44 patients (28.4%). The mean pulmonary arterial pressure at the time of catheterization was 54.9 ± 14.1 mmHg. Of 5 patients with CTEPH, 2 patients was diagnosed by lung angiography CT scan, 2 patients was diagnosed by ventilation/perfusion scan (V/Q scan), and 1 patients was diagnosed by both V/Q scan and lung angiography CT scan. One of 2 patient who diagnosed by V/Q scan, had normal lung angiography CT scan.

Conclusion: This study provides information on the demographic and clinical features of PH patients hospitalized in National Cardiovascular Center Harapan Kita (NCCHK). Most of the patients was female and young age. Congenital heart disease was the most frequent cause of PH in NCCHK.  Echocardiography is the most frequent tool used for diagnosis pulmonary hypertension.

KEYWORDS : pulmonary hypertension, hospitalized, demographic, clinical

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